US approves New metastatic Lung Cancer medicine
The US Food and Drug Administration (FDA) has approved the new cancer treatment medicine adagrasib for patients with end-stage lung cancer.
The FDA's decision was based on a clinical trial called KRYSTAL-1. Adagrasib is an oral medication, formulated to target genetic mutations called KRAS, which occurs in about 13% of cases of non-small cell lung cancer (NSCLC), the most common form of the disease.
Mirati is licensed to treat adult patients with advanced (invasive-metastatic) lung cancer determined by FDA-approved test method and has used at least 1 previous systemic therapy (including chemotherapy, vascular antibiotics and immunotherapy).
Following approval, stocks of the medicine maker Mirati Therapeutics rose 8%. According to Mirati, the medicine will be sold under the brand name Krazati for $19,750/bottle of 180 200-milligram tablets.
In addition to Krazati, another medicine that can inhibit KRAS gene mutations is Lumakras of Amgen Inc (USA). This medicine is used to treat patients with advanced stage lung cancer as second-priority treatment after first-priority treatment has failed.
Lung cancer is one of the three most common cancers and the leading cause of cancer death globally. Lung cancer is divided into two main types: small cell lung cancer which accounts for about 10-15% of lung cancer patients and non-small cell lung cancer which accounts for about 85%.
According to Seer Cancer statistics, about 6% of men and women will be diagnosed with lung cancer at some point in their lives. The median 5-year survival rate for lung cancer is 22.9%.
US approves New metastatic Lung Cancer medicine
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