AstraZeneca’s Drug proves effective in extending the Lifespan of Lung Cancer patients
On March 9, British-Swedish pharmaceutical company AstraZeneca announced that its cancer drug Imfinzi has proven to be effective in increasing the survival time of lung cancer patients. The drug, which is a form of immunotherapy, was able to significantly extend the lifespan of patients suffering from early-stage non-small cell lung cancer.
The clinical trial involved administering Imfinzi in combination with chemotherapy before surgery and subsequently as a standalone drug after surgery. The patients who underwent this treatment were able to live significantly longer without any recurrence of the disease. Imfinzi was approved by the FDA in 2017 for the treatment of certain types of bladder cancer and is seen as the latest immune system cancer therapy used in treating patients with lung cancer and urothelial carcinoma.
The AstraZeneca trial was conducted on lung cancer patients who were still able to remove their tumors surgically. The patients were given chemotherapy in conjunction with Imfinzi before surgery and only Imfinzi after surgery. The control group, on the other hand, was treated only with surgery combined with chemotherapy. The drug was found to be well-tolerated, with no significant concerns raised pre or postoperative.
The clinical success of Imfinzi is particularly significant for AstraZeneca since the drug had previously failed in a separate trial for patients with advanced non-small cell lung cancer. The trial results showed that the drug was less effective when used as a monotherapy compared to chemotherapy.
Immunotherapy drugs like Imfinzi work by enhancing the body's natural defense mechanisms against cancer cells. In combination with chemotherapy, they help to strengthen the immune system and target cancer cells more effectively. This approach offers a more sophisticated way of fighting cancer, particularly in cases where traditional chemotherapy has been found to be ineffective.
The trial's success is a significant breakthrough in oncology treatment, particularly as current treatment options for lung cancer patients are often limited. Immunotherapy drugs are seen as one of the few remaining treatment options for patients with this disease, and the AstraZeneca trial is seen as a major step forward in refining the use of these drugs in oncology.
AstraZeneca’s Drug proves effective in extending the Lifespan of Lung Cancer patients
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